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Gupta, Mahesh P.
Person
Why?
Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.
Academic Article
Why?
Cellular mechanisms promoting cachexia and how they are opposed by sirtuins 1.
Academic Article
Why?
Role of Sirtuins in Regulating Pathophysiology of the Heart.
Academic Article
Why?
Exploring roles of sirtuins in protecting diabetic hearts
Grant
Why?
Activation of sirtuins to prevent adverse cardiac remodeling after CABG
Grant
Why?
Sirtuins
Concept
Why?
The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy.
Academic Article
Why?
Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Academic Article
Why?
Is nuclear sirtuin SIRT6 a master regulator of immune function?
Academic Article
Why?
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Academic Article
Why?
Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth.
Academic Article
Why?
Posttranslational modification of Sirt6 activity by peroxynitrite.
Academic Article
Why?
Sirt1 and Sirt6 mediate beneficial effects of rosiglitazone on hepatic lipid accumulation.
Academic Article
Why?
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1.
Academic Article
Why?
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